TINJAUAN FITOKIMIA DAN AKTIVITAS ANTIDIABETES Cinnamomum zeylanicum Blume PADA DIABETES MELITUS TIPE 2 : LITERATUR REVIEW
DOI:
https://doi.org/10.30605/vz1wz004Keywords:
phytochemistry, antidiabetic, Cinnamomum zeylanicum, type 2 diabetes mellitusAbstract
Type 2 diabetes mellitus is a metabolic disorder with rapidly increasing global prevalence and a high burden of complications. Limitations of conventional therapies, including reduced efficacy and adverse effects, highlight the need for complementary approaches with multi-target actions. This study aimed to evaluate the phytochemical composition and antidiabetic potential of Cinnamomum zeylanicum as an adjunct therapy. A literature review was conducted on studies published between 2016 and 2026 retrieved from Google Scholar and ScienceDirect. The findings demonstrate that Cinnamomum zeylanicum is rich in bioactive compounds, particularly polyphenols, flavonoids, cinnamaldehyde, and eugenol, which exert glucose-lowering effects through multiple mechanisms, including inhibition of α-amylase and α-glucosidase, enhancement of insulin sensitivity, and antioxidant activity. Evidence from in vitro, in vivo, and clinical studies consistently indicates significant reductions in blood glucose levels and improvements in metabolic parameters. Overall, Cinnamomum zeylanicum shows strong potential as an effective adjunct therapeutic agent for type 2 diabetes mellitus
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