NARRATIVE REVIEW: POTENSI EKSTRAK BAWANG PUTIH (Allium sativum) DALAM MENINGKATKAN PERTUMBUHAN LACTOBACILLUS DAN MENGHAMBAT BAKTERI PENYEBAB DIARE

Authors

DOI:

https://doi.org/10.30605/khm94k57

Keywords:

Allium sativum, Antibacterial, Diarrhea, Lactobacillus, Prebiotic

Abstract

Diarrhea is a global health challenge exacerbated by increasing antibiotic resistance. This narrative review aims to analyze the potential of garlic extract (Allium sativum) as a natural synbiotic agent in supporting Lactobacillus growth while suppressing enteric pathogens. The method used was a narrative review with systematic literature searches through the Google Scholar and PubMed databases. The synthesis results show that garlic contains allicin and fructooligosaccharide (FOS) compounds at 3.34% w/w, which are effective in inhibiting pathogenic bacteria such as Escherichia coli and Salmonella spp., and are able to stimulate the growth of Lactobacillus acidophilus optimally at a concentration of 4%. In conclusion, Allium sativum has dual potential as an antibacterial agent and prebiotic, whose effectiveness is influenced by concentration and extraction method. Further research is needed to standardize the dosage for clinical application.

References

Abdel-hafeez, E. H., Ahmad, A. K., & Kamal, A. M. (2015). In vivo antiprotozoan effects of garlic ( Allium sativum ) and ginger ( Zingiber officinale ) extracts on experimentally infected mice with Blastocystis spp . 3439–3444. https://doi.org/10.1007/s00436-015-4569-x

Abdulrahman, M. Y., Ibrahim, N. A., Osman, M., Essa, A., Adam, S. Y., Mohai, R., Din, U., Jan, R. U., Basher, N. S., Rejili, M., Elnesr, S. S., Saleh, A. A., Husien, H. M., & Wang, M. (2026). Oral Administration of Lactobacillus amylovorus Alleviates Diarrhea by Restoring Gut Microbiota and SCFAs in Neonatal Goats. 1–20.

Adebolu, T. T., Odeoye, O. O., & Oyetayo, V. O. (2011). Effect of garlic ( Allium sativum ) on Salmonella typhi infection , gastrointestinal flora and hematological parameters of albino rats. 10(35), 6804–6808. https://doi.org/10.5897/AJB10.2598

Altuntas, S., & Korukluoglu, M. (2019). Growth and effect of garlic ( Allium sativum ) on selected beneficial bacteria. 2061(4), 897–904.

Andualem, B. (2013). antibacterial activity of stingless bee ( A pis mellipodae ) honey and garlic ( A llium sativum ) extracts against standard and clinical pathogenic bacteria C ombined. Asian Pacific Journal of Tropical Biomedicine, 3(9), 725–731. https://doi.org/10.1016/S2221-1691(13)60146-X

Bhatwalkar, S. B., Mondal, R., Babu, S., & Krishna, N. (2021). Antibacterial Properties of Organosulfur Compounds of Garlic ( Allium sativum ). 12(July), 1–20. https://doi.org/10.3389/fmicb.2021.613077

Enchev, S., Nenova, R., Penchev, P., & Ilieva, Y. (2025). APPLICATION OF MEDICINAL PLANTS , PROBIOTICS AND SYNBIOTIC PRODUCTS IN PREVENTIVE CARE AND ALTERNATIVE THERAPY FOR FARM ANIMALS IN MODERN VETERINARY MEDICINE . A REVIEW. LXVIII(1), 226–233.

Fadare, O. S., Singh, V., Enabulele, O. I., Shittu, O. H., & ... (2022). In vitro evaluation of the synbiotic effect of probiotic Lactobacillus strains and garlic extract against Salmonella species. In LWT. Elsevier. https://www.sciencedirect.com/science/article/pii/S0023643821015929

H, M. M. (2025). The Role of Phytotherapy in Supporting Gut Health for Diarrhea Management. 28–35.

Johnson, M., & Olaleye, O. N. (2016). Antimicrobial and Antioxidant Properties of Aqueous Garlic ( Allium sativum ) Extract against Staphylococcus aureus and Pseudomonas aeruginosa. 14(1), 1–11. https://doi.org/10.9734/BMRJ/2016/24095

Kubba, M. A., Hussein, S. M., & Al-zaidi, O. S. (2021). The Effect Allium sativum ( Garlic Extract ) as Prebiotic Substance on the Activity of Probiotic Bacteria Lactobacillus acidophilus Against Some Locally Isolates of Pathogenic Bacteria. 15(2), 387–394.

Kumar, P., Yadav, J., Jain, M., & Yadav, P. (2016). Bactericidal Efficacy of Allium sativum ( garlic ) Against Multidrug Resistant Vibrio cholerae O1 Epidemic Strains. 66(5), 479–484.

Mwachofi, F. N., Mwangi, A., Macharia, C., & Nyamache, K. (2025). Antimicrobial Activity of Zinc Oxide Nanoparticles and Allium. 9(2), 401–409.

Nugroho. (2024). Journal of Nusantara Education. Journal of Nusantara Education, 4(1), 1–13.

Satora, M., Magdziarz, M., Rz, A., Rypu, K., & Katarzyna, P. (2020). Insight into the intestinal microbiome of farrowing sows following the administration of garlic ( Allium sativum ) extract and probiotic bacteria cultures under farming conditions. 1–18.

Sunu, P., Sunarti, D., Mahfudz, L. D., & Yunianto, V. D. (2019). Prebiotic activity of garlic ( Allium sativum ) extract on Lactobacillus acidophilus. 12, 2046–2051.

Taş, E., Erginkaya, Z., Kalkan, S., & Turhan, E. Ü. (2017). Turkish Journal of Agriculture - Food Science and Technology Determination of Antimicrobial Effects of Probiotic Lactic Acid Bacteria and Garlic Extract Against Some Foodborn Pathogenic Bacteria. 5(2), 125–131.

Yin, Z., Wang, K., Liu, Y., Li, Y., He, F., Yin, J., & Tang, W. (2024). Lactobacillus johnsonii Improves Intestinal Barrier Function and Reduces Post-Weaning Diarrhea in Piglets : Involvement of the.

Zhao, W., Wang, J., Zhang, M., Wu, S., Dai, W., Yang, X., & Wang, H. (2021). Global burden of diarrhea disease in the older adult and its attributable risk factors from to : a comprehensive analysis from the global burden of disease study.

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Published

2026-03-25

Issue

Vol. 11 No. 1 (2026): Volume 11, no 1, 2026, (Januari - Maret 2026)

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Copyright (c) 2026 Fadillah Amanda, Olyvia Azzahra Putri Hartono

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How to Cite

NARRATIVE REVIEW: POTENSI EKSTRAK BAWANG PUTIH (Allium sativum) DALAM MENINGKATKAN PERTUMBUHAN LACTOBACILLUS DAN MENGHAMBAT BAKTERI PENYEBAB DIARE. (2026). Jurnal Biogenerasi, 11(1), 397-407. https://doi.org/10.30605/khm94k57