FORMULASI SEDIAAN OBAT KUMUR KOMBINASI EKSTRAK DAUN GAMBIR (Uncraina gambir (Hunter) Roxb) dan BIJI PINANG (Areca catechu L.) SEBAGAI ANTIBAKTERI

Authors

  • Dini Mardhiyani a:1:{s:5:"en_US";s:20:"Universitas Abdurrab";}

DOI:

https://doi.org/10.30605/biogenerasi.v8i1.2216

Keywords:

Gambier, Areca Nut, Mouthwash

Abstract

Bad breath (Halitosis) is one of the oral health problems that many people complain about after caries and periodontal disease. Plants that have the potential to be used as mouthwash preparations are gambier leaves and areca nut seeds. The content of phenol and catechin compounds has the ability as a bactericidal. Meanwhile, areca nut has the ability to inhibit the release of calcium ions in the tooth demineralization process stimulated by Streptococcus mutans. This study aims to determine the evaluation results of a combination of gambier leaf and areca nut mouthwash preparations with concentrations of 0.5%, 1%, and 1.5% with several physical parameters, namely organoleptic tests, pH tests, clarity tests, and viscosity tests. Physical stability testing was carried out on Day 0 and Day 7. The results of the organoleptic test are liquid, odorless, white and yellowish brown, sweet and bitter taste. ptest day 0 on controls, F1, F2, and F3, namely 6.2, 4.8, 4.8, 4.6, and day 7 on controls, F1, F2, and F3, namely 6.2, 4 ,7, 4,6, 4,4. Clarity test on day 0 and day 7 controls, F1, F2, and F3 were clear. Viscosity test day 0 on controls, F1, F2, and F3, namely 11.40 cPoises, 9.88 cPoises, 7,271 cPoises, 10.13 cPoises and day 7 on controls, F1, F2, and F3, namely 7,725 cPoises, 9,380 cPoises, 10,218 cPoises, 11 cPoises.

Downloads

Download data is not yet available.

References

Claffey, N. (2003). Essential oil mouthwashes: a key component in oral health management. Journal of clinical periodontology, 30, 22-24.
Fitriansyah, S. N., Wirya, S., & Hermayanti, C. (2016). Formulasi dan evaluasi spray gel fraksi etil asetat pucuk daun teh hijau (Camelia sinensis [L.] Kuntze) sebagai antijerawat. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 13(02), 202-216.
Handayani, F., Sundu, R., & Sari, R. M. (2017). Formulasi dan uji aktivitas antibakteri streptococcus mutans dari sediaan mouthwash ekstrak daun jambu biji (Psidium guajava L.). Jurnal Sains dan Kesehatan, 1(8), 422-433.
Lachman, L., Lieberman, H., and Kanig, J. L. (1994). Teori Dan Praktek Farmasi Industri II (Edisi 3). Jakarta: Penerbit Universitas Indonesia.
Lachman. 2017. Teori dan praktek farmasi industry 2. edisi ketiga. Universitas Indonesia Press Jakarta.
Lucida, H., Bakhtiar, A., and Putri, W. A. 2007. Formulasi Sediaan Antiseptik Mulut Dari Katekin Gambir. Jurnal Sains Teknologi Farmasi. Vol 12. No (1). Hal. 1-7
Lukas, A. (2012). Formulasi obat kumur gambir dengan tambahan peppermint dan minyak cengkeh. Jurnal Dinamika Penelitian Industri, 23(2), 67-76.
Martin, A., Swarbrick J., and Cammarata, A. 1993. Farmasi Fisik Dasar-Dasar Kimia Fisik dalam ilmu Farmasetik. Edisi III. Universitas Indonesia Press. Jakarta.
Noval, N., Melviani, M., Novia, N., & Syahrina, D. (2020). Formulasi Dan Evaluasi Sediaan Obat Kumur (Mouthwash) Dari Ekstrak Etanol Tanaman Bundung (Actinoscirpus Grossus) Sebagai Antiseptik Mulut. Jurnal Surya Medika (JSM), 6(1), 112-120.
Nurjannah, I., Stevani, H., & Dewi, R. (2018). Aktivitas Perasan Biji Pinang (Areca catechu L.) Terhadap Pertumbuhan Streptococcus Mutans. Media Farmasi, 14(2), 72-77.
Pontefract, H., Hughes, J., Kemp, K., Yates, R., Newcombe, R. G., & Addy, M. (2001). The erosive effects of some mouthrinses on enamel: a study in situ. Journal of clinical periodontology, 28(4), 319-324.
Pradewa, M. R. (2008). Formulasi sediaan obat kumur berbahan dasar gambir (Uncraina gambir (Hunter) roxb). IPB (Bogor Agricultural University).
Rasyadi, Y., Yenti, R., & Jasril, A. P. (2019). Formulasi dan Uji Stabilitas Fisik Sabun Mandi Cair Ekstrak Etanol Buah Kapulaga (Amomum compactum Sol. ex Maton). PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 16(2), 188-198.
Rosa, Y. (2021). Aktivitas Antijamur Ekstrak Etanol Daun Gambir (Uncaria Gambir Roxb) Terhadap Candida albicans. Jurnal Ilmu Kedokteran dan Kesehatan, 8(3).
Rowe, R. C., Sheskey, P., & Quinn, M. (2009). Handbook of pharmaceutical excipients. Libros Digitales-Pharmaceutical Press.
Rowe, R. C., Sheskey, P., and Quinn, M. 2009. Handbook of Pharmaceutical Excipients. 6th edn. London : American Pharmaceutical Association.
Septiani, D., Yuslianti, E. R., & Nasroen, S. L. (2015). Pengaruh Ekstrak Etanol Daun Gambir (Uncaria Gambir) Dibandingkan Dengan Chlorhexidine Gluconate 0, 2% Topikal Terhadap Penyembuhan Luka Mukosa Palatum Tikus Galur Wistar: Effect Of Ethanol Gambir Leaves (Uncaria Gambir) Compared With Chlorhexidine Gluconate 0, 2% Topical For Wound Healing On Palate Mucosal Galur Wistar Rat. Dentika: Dental Journal, 18(3), 262-267.
Tranggono R.I., dan Latifa F. 2007. Buku Pegangan Ilmu Pengetahuan Kosmetik. PT. Gramedia Pustaka Utama. Jakarta; Hal. 11, 90-93, 167.

Downloads

Published

2023-02-09

How to Cite

Mardhiyani, D. (2023). FORMULASI SEDIAAN OBAT KUMUR KOMBINASI EKSTRAK DAUN GAMBIR (Uncraina gambir (Hunter) Roxb) dan BIJI PINANG (Areca catechu L.) SEBAGAI ANTIBAKTERI. Jurnal Biogenerasi, 8(1), 343–349. https://doi.org/10.30605/biogenerasi.v8i1.2216

Issue

Vol. 8 No. 1 (2023): Volume 8 Nomor 1 Tahun 2023

Section

Articles

License

In submitting the manuscript to the journal, the authors certify that:

  • They are authorized by their co-authors to enter into these arrangements.
  • The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
  • That it is not under consideration for publication elsewhere,
  • That its publication has been approved by all the author(s) and by the responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
  • They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
  • They agree to the following license and copyright agreement.

License and Copyright Agreement

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.